The X-Men are a group of superhero mutants led and founded by Professor Charles Xavier aka Professor X.
Its early history is unknown, but it was mentioned that the X-Men was formed by Charles Xavier to save the world from threats that may shatter mutant-human relationship and prevented a catastrophic war that exterminates almost all mutants and humans alike leaving the machines left in the world from happening despite being hounded and hunted down by the M.R.D. (Mutant Response Division) an anti-mutant special US military unit.
- Wolverine is the only X-Men seen as a member of the Howling Commandos during World War II.
- These are the same X-Men from the TV series Wolverine and the X-Men, as they take place in the same universe.
- Concept art for a proposed third season implied that there would have been a episode where the X-Men team up with the Avengers.
- According To Christopher Yost, if there was a third season of EMH, the second half would have introduced The X-Men. It would have focused on Avengers Vs. X-Men, where The Phoenix would have played a major role.